Intelligent Light

See Beyond the Visible

ActivSight™ Intelligent Light is the first and only modular form-factor with multimodal Advanced Visualization. ActivSight allows surgeons to augment their senses using augmented reality overlays.

Patents 10,925,465 and 11,206,991

Enhanced  Patient Care

Critical structure identification and tissue perfusion assessment are essential for patients to have the best possible chance of healing well without facing life-threatening or costly complications.

Surgeons can “see” otherwise imperceptible tissue perfusion with ActivPerfusion™ Mode. ActivICG™ Mode allows surgeons to visualize ICG (Indocyanine Green) in critical structures, such as bile ducts, using familiar techniques.

View ActivSight Bibliography

Real-Time Data

ActivSight’s Intelligent Light provides advanced visualization in real-time.

Designed with ease of use in mind, surgeons are able to access ActivPerfusion Mode with the push of a button and instantaneously see blood flow. Real-time data allows surgeons to quickly assess tissue perfusion and make important decisions.

Designed to address the most serious, costly patient complications.1-19

With the press of a button, switch between multiple modes of advanced intraoperative visualization.

See the Unseen

with ActivSight

MIS System Compatible

Advanced visualization should be available to every patient who stands to benefit from it, and our business model reflects this.

Designed to be a routine part of surgical practice, ActivSight is engineered to work with existing laparoscopic and robotic systems. ActivSight requires no capital purchase with a subscription based cost of ownership.

Contact your Activ Surgical Rep for a current list of compatible systems.

ActivSight™ Enhanced Intraoperative Visualization

A bibliography of published clinical data and abstracts.

Tully S, Oberlin J, DeMaio E, Dehghani H, O’Shea L, Calef T, Kim PC. Superior efficacy and utility of ActivSight laser speckle imaging to Indocyanine Green (ICG)-based fluorescence imaging in visualizing in vivo tissue perfusion and vasculature. Society of American Gastrointestinal and Endoscopic Surgeons 2020 Meeting

Nwaiwu CA, Shah SK, Bajwa KS, Agarwal, AK, Felinski MM, Walker PA, Wilson TD, Holihan JL, Akhtar SJ, Kudav V, Rachlin EK, Rivera AR, Klein CL, Dechert AF, Buharin VE, Kim PCW, Wilson EB. First Thirty-Four Consecutive Patients Using De Novo Laparoscopy-Compatible Real-time Imaging Device Combining Laser Speckle Contrast Imaging and Near-infrared Fluorescence (NIRF) in Colorectal and Bariatric Surgery, and Laparoscopic Cholecystectomy (LC). Society of American Gastrointestinal and Endoscopic Surgeons 2021. Presentation date: August 31 –September 3, 2021

Nwaiwu CA, Buharin VE, Mach A, Grandl R, Dechert AF, O’Shea LJ, Schwaitzberg SD, Kim PCW. Feasibility And Comparison of Laparoscopic Laser Speckle Contrast Imaging (LSCI) To Near-infrared (NIR) Display of Indocyanine Green (ICG) In Intraoperative Tissue Blood Flow/Tissue Perfusion and Extrahepatic Bile Ducts in Preclinical Porcine Models. American College of Surgeons Clinical Congress 2021. Presentation date: October 23, 2021

Shah SK, Nwaiwu CA, Agarwal AK, Bajwa KS, Felinksi MM, Walker PA, Wilson TD, Dechert AF, Kim PCW, Wilson EB. First-In-Human (FIH) Safety, Feasibility, & Usability Trial (NCT# 04633512) Of A Laparoscopic Imaging Device Using Laser Speckle Contrast Imaging (LSCI) Visualizing Real-Time Tissue Perfusion and Blood Flow Without Fluorophore in Colorectal and Bariatric Patients. American College of Surgeons Clinical Congress 2021. Presentation date: October 24, 2021

Noel JP, Mascarenhas A, Nwaiwu CA, Liu YZ, Buharin VE, Oberlin J, Dechert AF, Kim PCW, Patel V. ActivSight Laser Speckle Contrast Imaging Compared to Indocyanine Green in Renal Perfusion of an Animal Model. European Robotic Urologic Society 2021.

Sanders CM, Nwaiwu CA, Liu YZ, Panchal AN, Butsch JL, Hoffman AB, Posner AR, Falvo MA, Visco J, Ortolani JB, Barone SM, Burstein MD, DeJesus C, Bouvy ND, Boni L, Shah SK, Wilson EB, Dechert AF, Buharin VE, Schwaitzberg SD, Kim PCW. ActivSightTM Dye-less Visualization of Tissue Perfusion in MIS Surgery: Interim Analysis of First Clinical (n=66) and Preclinical (n=20) Studies with ICG Comparison. World Congress of Endoscopic Surgery/ European Association of Endoscopic Surgery 2021. Presentation date: November 24, 2021

Noel JP, Mascarenhas A, Nwaiwu CA, Liu YZ, Buharin VE, Oberlin J, Dechert AF, Kim PWC, Patel V. ActivSight Laser Speckle Contrast Imaging Compared to Indocyanine Green in Renal Perfusion of an Animal Model. American Urologic Association 2022.

Boni, L. A novel visualisation system. European Association for Endoscopic Surgery Midwinter Meeting 2022.

Mehrotra S, Liu YZ, Nwaiwu CA, Buharin VE, Oberlin J, Stolyarov R, Schwaitzberg SD, Kim PCW. Potential Clinical Utility of Real-Time Tissue Perfusion Quantification Using Laparoscopic Laser Speckle Contrast Imaging (LSCI) and Differential Responses to Arterial Versus Venous Occlusion in Porcine Intestine Model. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Presentation date: March 16, 2022

Liu YZ, Nwaiwu CA, Dechert AF, Mehrotra S, Shah SK, King ML, Schwaitzberg SD, Kim PCW, Wilson EB. Utility and Usability of Laser Speckle Contrast Imaging (LSCI) for Displaying Real-time Tissue Perfusion/Blood flow in Robot Assisted Surgery (RAS): Comparison to Indocyanine Green (ICG) Use and in Laparoscopic Surgery. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Presentation date: March 17, 2022

Rai, A; James, J; Richstone, A; Kavoussi, L. Evaluating Utility and Efficacy of Laser Speckle Imaging for Visualizing Perfusion During Urologic Surgery. Engineering and Urology Society 2022.

Nwaiwu CA, Liu YZ, Mehrotra S, Wilson EB, Schwaitzberg SD, Park A, Kalady MF, Kim PCW. ActivSightTM: Real-time, Dye-Free Visualization of Bowel Perfusion Using Laser Speckle Contrast Imaging. American Society of Colon and Rectal Surgeons 2022. Presentation date: May 1, 2022

Liu YZ, Mehrotra S, Stolyarov R, Nwaiwu CA, Oberlin J, Schwaitzberg SD, Kalady MF, Kim PCW. Quantifying Real-Time Bowel Perfusion & Distinguishing Arterial/Venous Obstruction using Laser Speckle Contrast Imaging (LSCI). American Society of Colon and Rectal Surgeons 2022. Presentation date: May 3, 2022

Agarwal AK, Nwaiwu CA, Mehrotra S, Liu YZ, Sanders CM, Falvo MA, Wilson EB, Shah SK. Usability of Laser Speckle Contrast Imaging for Perfusion Assessment: First 17 Colectomy Patients. American Society of Colon and Rectal Surgeons 2022. Presentation date: April 30- May 4, 2022

Mehrotra S, Liu YZ, Stolyarov R, Nwaiwu CA, Oberlin J, Schwaitzberg SD, Kim PC. Perfusion Difference in antimesenteric & mesenteric bowel with Laser Speckle Contrast Imaging. American Society of Colon and Rectal Surgeons 2022. E-poster.

Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Filicori F, Wilson E, Kim PCW. Dye-less, Real-time Visualization of Tissue Perfusion in Porcine Gastric Tube Model using Laser Speckle Contrast Imaging (LSCI) and Laser Doppler Imaging (LDI). American Society for Metabolic and Bariatric Surgery 2022. Presentation date: June 9, 2022.

Mehrotra S, Liu YZ, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Filicori F, Schwaitzberg SD, Wilson EB, Bouvy ND, Kim PCW. Relative Perfusion Response of Gastric Tube to Aortic and Portal Vein Occlusion Measured by Laser Speckle Contrast Imaging (LSCI) in Porcine Model. American Society for Metabolic and Bariatric Surgery 2022. E-poster.

Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Bouvy ND, Kim PCW. Comparing Real-time Quantification of Tissue Perfusion using Laser Speckle Contrast Imaging to Laser Doppler Imaging in Porcine Intestinal Anastomosis. European Association of Endoscopic Surgery 2022. Presentation date: July 6, 2022.

Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Chand M, Bouvy ND, Boni L, Kim PCW. Comparing Real-time Tissue Perfusion Assessment between Laser Speckle Contrast Imaging and Indocyanine Green Fluorescence in Porcine Small Intestine. European Association of Endoscopic Surgery 2022 – Amazing Technologies Session. Presentation date: July 5, 2022.

Chibueze A. Nwaiwu, Mahdi Al-Taher, Roman Stolyarov, Yao Z. Liu, Saloni Mehrotra, Rainer Kimmig, Benjamin Weixler, Hans F. Fuchs, Manish Chand, Kai Nowak, Luigi Boni, Adrian E. Park, Nicole Bouvy. Quantifying Tissue Perfusion Using Laser Speckle Contrast Imaging and Correlation with Local Tissue Capillary Lactate. European Association of Endoscopic Surgery 2022 – Amazing Technologies Session. Presentation date: July 5, 2022.

Liu YZ, Nwaiwu CA, Dechert AF, Mehrotra S, Shah SK, King ML, Schwaitzberg SD, Kim PCW, Wilson EB. Utility and Usability of Laser Speckle Contrast Imaging (LSCI) for Displaying Real-time Tissue Perfusion/Blood flow in Robot Assisted Surgery (RAS): Comparison to Indocyanine Green (ICG) Use and in Laparoscopic Surgery. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Accepted in Surgical Endoscopy on July 4, 2022.

“Real-time intelligence and advanced imaging—including the visualization of tissue perfusion during surgery—is critical to improving patient outcomes.”

- Adrian Park, MD,

Chair of Surgery, Surgeon in Chief, Luminis Health

Professor of Surgery, Johns Hopkins University

“ActivSight Perfusion Mode helped demonstrate real time blood supply which was reproducible and thus felt like something I could rely on to make decisions.”

– Adekemi Egunsola, MD

Northwell Health Physician Partners Center for Colon and Rectal Diseases